Á lódáil...
Mdm2 Promotes Genetic Instability and Transformation Independent of p53
Mdm2, a regulator of the tumor suppressor p53, is frequently overexpressed in human malignancies. Mdm2 also has unresolved, p53-independent functions that contribute to tumorigenesis. Here, we show that increased Mdm2 expression induced chromosome/chromatid breaks and delayed DNA double-strand break...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Microbiology (ASM)
2008
|
| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2493369/ https://ncbi.nlm.nih.gov/pubmed/18541670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01584-07 |
| Clibeanna: |
Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!
|