Intraluminal proteolytic activation plays an important role in replication of type 1 reovirus in the intestines of neonatal mice.

Oral inoculation of suckling mice with reovirus serotype 1 (strain Lang) results in the conversion of intact virions to intermediate subviral particles (ISVPs) in the intestinal lumen. Digestion of virus in vitro with chymotrypsin or trypsin reveals two distinct forms of ISVPs, while the predominant...

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Detaylı Bibliyografya
Yayımlandı:	J Virol
Asıl Yazarlar:	Bass, D M, Bodkin, D, Dambrauskas, R, Trier, J S, Fields, B N, Wolf, J L
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 1990
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249324/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157065/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.4.1830-1833.1990
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Intraluminal proteolytic activation plays an important role in replication of type 1 reovirus in the intestines of neonatal mice.

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