MglA and Igl Proteins Contribute to the Modulation of Francisella tularensis Live Vaccine Strain-Containing Phagosomes in Murine Macrophages

The Francisella tularensis live vaccine strain (LVS), in contrast to its iglC mutant, replicates in the cytoplasm of macrophages. We studied the outcome of infection of the murine macrophagelike cell line J774A.1 with LVS and with iglC, iglD, and mglA mutants, the latter of which is deficient in a g...

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Bibliographic Details
Main Authors: Bönquist, Linda, Lindgren, Helena, Golovliov, Igor, Guina, Tina, Sjöstedt, Anders
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493230/
https://ncbi.nlm.nih.gov/pubmed/18474647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00226-08
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