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Impaired Opsonization with C3b and Phagocytosis of Streptococcus pneumoniae in Sera from Subjects with Defects in the Classical Complement Pathway

Results from studies using mice deficient in specific complement factors and clinical data on patients with an inherited deficiency of the classical complement pathway component C2 suggest that the classical pathway is vital for immunity to Streptococcus pneumoniae. However, the consequences of defe...

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Autors principals: Yuste, Jose, Sen, Ashwin, Truedsson, Lennart, Jönsson, Göran, Tay, Liang-Seah, Hyams, Catherine, Baxendale, Helen E., Goldblatt, Fiona, Botto, Marina, Brown, Jeremy S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493217/
https://ncbi.nlm.nih.gov/pubmed/18541650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00291-08
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