Impaired Opsonization with C3b and Phagocytosis of Streptococcus pneumoniae in Sera from Subjects with Defects in the Classical Complement Pathway

Results from studies using mice deficient in specific complement factors and clinical data on patients with an inherited deficiency of the classical complement pathway component C2 suggest that the classical pathway is vital for immunity to Streptococcus pneumoniae. However, the consequences of defe...

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Bibliographische Detailangaben
Hauptverfasser: Yuste, Jose, Sen, Ashwin, Truedsson, Lennart, Jönsson, Göran, Tay, Liang-Seah, Hyams, Catherine, Baxendale, Helen E., Goldblatt, Fiona, Botto, Marina, Brown, Jeremy S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493217/
https://ncbi.nlm.nih.gov/pubmed/18541650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00291-08
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