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Identification of Mutations Related to Streptomycin Resistance in Clinical Isolates of Mycobacterium tuberculosis and Possible Involvement of Efflux Mechanism

The MIC for streptomycin in the presence of efflux pump (EP) inhibitors and the sequencing of rpsL, rrs, and gidB genes provided evidence for the possible participation of EP in low-level streptomycin (STR) resistance of some isolates without mutations. Mutation in the gidB gene and an EP could act...

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Detalhes bibliográficos
Main Authors: Spies, Fernanda S., Almeida da Silva, Pedro E., Ribeiro, Marta O., Rossetti, Maria Lucia, Zaha, Arnaldo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493096/
https://ncbi.nlm.nih.gov/pubmed/18541729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01570-07
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