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Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes

OBJECTIVE: Epidemiological studies have linked vitamin D deficiency with the susceptibility to type 1 diabetes. Higher levels of the active metabolite, 1α,25-dihydroxyvitamin D, could protect from immune destruction of the pancreatic β cells. 1α,25-dihydroxyvitamin D is derived from its precursor 25...

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Autori principali: Bailey, Rebecca, Cooper, Jason D., Zeitels, Lauren, Smyth, Deborah J., Yang, Jennie H.M., Walker, Neil M., Hyppönen, Elina, Dunger, David B., Ramos-Lopez, Elizabeth, Badenhoop, Klaus, Nejentsev, Sergey, Todd, John A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493063/
https://ncbi.nlm.nih.gov/pubmed/17606874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-0652
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