TAK, an HIV Tat-associated kinase, is a member of the cyclin-dependent family of protein kinases and is induced by activation of peripheral blood lymphocytes and differentiation of promonocytic cell lines

We have previously identified a cellular protein kinase activity termed TAK that specifically associates with the HIV types 1 and 2 Tat proteins. TAK hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II in vitro in a manner believed to activate transcription [He...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Yang, Xinzhen, Gold, Moses O., Tang, Derek Ng, Lewis, Dorothy E., Aguilar-Cordova, Estuardo, Rice, Andrew P., Herrmann, Christine H.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1997
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24930/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9356449/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.23.12331
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