Caspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiation

Caspases have demonstrated several non-apoptotic functions including a role in the differentiation of specific cell types. Here, we show that caspase-8 is the upstream enzyme in the proteolytic caspase cascade whose activation is required for the differentiation of peripheral blood monocytes into ma...

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Detalhes bibliográficos
Main Authors: Rébé, Cédric, Cathelin, Séverine, Launay, Sophie, Filomenko, Rodolphe, Prévotat, Laurent, L'Ollivier, Coralie, Gyan, Emmanuel, Micheau, Olivier, Grant, Steven, Dubart-Kupperschmitt, Anne, Fontenay, Michaëla, Solary, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492986/
https://ncbi.nlm.nih.gov/pubmed/17047155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-011585
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