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The structural basis of proteolytic activation of bovine glutamate dehydrogenase

In this work, we re-examine the previously reported phenomenon of the creation of a superactive glutamate dehydrogenase by proteolytic modification by chymotrypsin and explore the various discrepancies that came to light during those studies. We find that superactivation is caused by cleavage at the...

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Detalhes bibliográficos
Main Authors: Carrigan, John B., Engel, Paul C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492812/
https://ncbi.nlm.nih.gov/pubmed/18467497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.034785.108
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