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Intragenotypic JFH1 based recombinant hepatitis C virus produces high levels of infectious particles but causes increased cell death

The full-length hepatitis C virus (HCV) JFH1 genome (genotype 2a) produces moderate titers of infectious particles in cell culture but the optimal determinants required for virion production are unclear. It has been shown that intragenotypic recombinants encoding core to NS2 from J6CF in the context...

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Detalhes bibliográficos
Main Authors: Mateu, Guaniri, Donis, Ruben O., Wakita, Takaji, Bukh, Jens, Grakoui, Arash
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492671/
https://ncbi.nlm.nih.gov/pubmed/18455749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.03.027
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