Endothelial nitric oxide synthase regulates N-Ras activation on the Golgi complex of antigen-stimulated T cells

Ras/ERK signaling plays an important role in T cell activation and development. We recently reported that endothelial nitric oxide synthase (eNOS)-derived NO regulates T cell receptor (TCR)-dependent ERK activation by a cGMP-independent mechanism. Here, we explore the mechanisms through which eNOS e...

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Detalhes bibliográficos
Main Authors: Ibiza, Sales, Pérez-Rodríguez, Andrea, Ortega, Ángel, Martínez-Ruiz, Antonio, Barreiro, Olga, García-Domínguez, Carlota A., Víctor, Víctor M., Esplugues, Juan V., Rojas, José M., Sánchez-Madrid, Francisco, Serrador, Juan M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492470/
https://ncbi.nlm.nih.gov/pubmed/18641128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711062105
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