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A positive-feedback mechanism promotes reovirus particle conversion to the intermediate associated with membrane penetration

Membrane penetration by reovirus is associated with conversion of a metastable intermediate, the ISVP, to a further-disassembled particle, the ISVP*. Factors that promote this conversion in cells are poorly understood. Here, we report the in vitro characterization of a positive-feedback mechanism fo...

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Autori principali: Agosto, Melina A., Myers, Kimberly S., Ivanovic, Tijana, Nibert, Max L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492467/
https://ncbi.nlm.nih.gov/pubmed/18653761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802039105
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