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Requirements for the Formation of Membrane Pores by the Reovirus Myristoylated μ1N Peptide

The outer capsid of the nonenveloped mammalian reovirus contains 200 trimers of the μ1 protein, each complexed with three copies of the protector protein σ3. Conformational changes in μ1 following the proteolytic removal of σ3 lead to release of the myristoylated N-terminal cleavage fragment μ1N and...

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Autors principals: Zhang, Lan, Agosto, Melina A., Ivanovic, Tijana, King, David S., Nibert, Max L., Harrison, Stephen C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704788/
https://ncbi.nlm.nih.gov/pubmed/19439475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00377-09
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