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Fusion function of the Semliki Forest virus spike is activated by proteolytic cleavage of the envelope glycoprotein precursor p62.

The precursor protein p62 of the prototype alphavirus Semliki Forest virus (SFV) undergoes during transport to the cell surface a proteolytic cleavage to form the mature envelope glycoprotein E2. To investigate the biological significance of this cleavage event, single amino acid substitutions were...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Lobigs, M, Garoff, H
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1990
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249238/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2304141/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.3.1233-1240.1990
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