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An intragenic revertant of a poliovirus 2C mutant has an uncoating defect.

A revertant was isolated from a temperature-sensitive poliovirus 2C mutant, 2C-31, which is defective in viral RNA synthesis. This revertant, called 2C-31R1, grew well at 39 degrees C and was not defective in RNA synthesis. However, in contrast to its parental mutant, 2C-31R1 was cold sensitive and...

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Библиографические подробности
Опубликовано в::J Virol
Главные авторы: Li, J P, Baltimore, D
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1990
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249223/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2154595/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.3.1102-1107.1990
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