An intragenic revertant of a poliovirus 2C mutant has an uncoating defect.

A revertant was isolated from a temperature-sensitive poliovirus 2C mutant, 2C-31, which is defective in viral RNA synthesis. This revertant, called 2C-31R1, grew well at 39 degrees C and was not defective in RNA synthesis. However, in contrast to its parental mutant, 2C-31R1 was cold sensitive and...

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Pubblicato in:	J Virol
Autori principali:	Li, J P, Baltimore, D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249223/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2154595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.3.1102-1107.1990
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