International Life Sciences Institute (Health and Environmental Sciences Institute, HESI) initiative on moving towards better predictors of drug-induced torsades de pointes

Knowledge of the cardiac safety of emerging new drugs is an important aspect of assuring the expeditious advancement of the best candidates targeted at unmet medical needs while also assuring the safety of clinical trial subjects or patients. Present methodologies for assessing drug-induced torsades...

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Hlavní autoři: Bass, A S, Darpo, B, Breidenbach, A, Bruse, K, Feldman, H S, Garnes, D, Hammond, T, Haverkamp, W, January, C, Koerner, J, Lawrence, C, Leishman, D, Roden, D, Valentin, J P, Vos, M A, Zhou, Y-Y, Karluss, T, Sager, P
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2008
Témata:
Themed Section Commentary
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492102/
https://ncbi.nlm.nih.gov/pubmed/18663380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.279
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