Transcriptionally active genome regions are preferred targets for retrovirus integration.

We have analyzed the transcriptional activity of cellular target sequences for Moloney murine leukemia virus integration in mouse fibroblasts. At least five of the nine random, unselected integration target sequences studied showed direct evidence for transcriptional activity by hybridization to nuc...

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Bibliographic Details
Main Authors: Scherdin, U, Rhodes, K, Breindl, M
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC249188/
https://ncbi.nlm.nih.gov/pubmed/2296087
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