Substitutions in the protease (3Cpro) gene of poliovirus can suppress a mutation in the 5' noncoding region.

The poliovirus mutant 5NC-11 has a 4-base insertion at position 70 within the 5' untranslated region and is deficient in RNA synthesis. Revertants from 5NC-11 were isolated, showing a partial recovery of wild-type levels of RNA synthesis. The 5' noncoding region of those revertants contained the mut...

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Vydáno v:	J Virol
Hlavní autoři:	Andino, R, Rieckhof, G E, Trono, D, Baltimore, D
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1990
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249150/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153227/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.607-612.1990
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