Substitutions in the protease (3Cpro) gene of poliovirus can suppress a mutation in the 5' noncoding region.
The poliovirus mutant 5NC-11 has a 4-base insertion at position 70 within the 5' untranslated region and is deficient in RNA synthesis. Revertants from 5NC-11 were isolated, showing a partial recovery of wild-type levels of RNA synthesis. The 5' noncoding region of those revertants contained the mut...
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| Udgivet i: | J Virol |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1990
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249150/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153227/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.607-612.1990 |
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