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Conserved RNA secondary structures promote alternative splicing

Pre-mRNA splicing is carried out by the spliceosome, which identifies exons and removes intervening introns. Alternative splicing in higher eukaryotes results in the generation of multiple protein isoforms from gene transcripts. The extensive alternative splicing observed implies a flexibility of th...

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Detalhes bibliográficos
Main Authors: Shepard, Peter J., Hertel, Klemens J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2491482/
https://ncbi.nlm.nih.gov/pubmed/18579871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1069408
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