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The adenovirus type 5 i-leader open reading frame functions in cis to reduce the half-life of L1 mRNAs.

The 440-nucleotide adenovirus type 5 i-leader sequence, encoding a 13.6-kilodalton protein, is located between the second and third components of the tripartite leader sequence. It appears primarily on the L1 family of mRNAs. To study its function, we constructed two point mutations within the i lea...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Soloway, P D, Shenk, T
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249143/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2296076/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.551-558.1990
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