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The adenovirus type 5 i-leader open reading frame functions in cis to reduce the half-life of L1 mRNAs.

The 440-nucleotide adenovirus type 5 i-leader sequence, encoding a 13.6-kilodalton protein, is located between the second and third components of the tripartite leader sequence. It appears primarily on the L1 family of mRNAs. To study its function, we constructed two point mutations within the i lea...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Soloway, P D, Shenk, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1990
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249143/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2296076/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.551-558.1990
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