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Three domains in the simian virus 40 core origin orchestrate the binding, melting, and DNA helicase activities of T antigen.

The simian virus 40 (SV40) core origin of replication consists of three functional domains. The sequence 5'-CACTACTTCTGGAATAG-3' with an imperfect inverted repeat (underlined), a palindrome with four 5'-GAGGC-3' pentanucleotide repeats, and a 17-base-pair A + T-rich segment. We have been able to ass...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Parsons, R, Anderson, M E, Tegtmeyer, P
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1990
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249138/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153220/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.2.509-518.1990
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