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Increased accumulation of chloroquine and desethylchloroquine in homozygous sickle cells
The effect of haemoglobin genotype on the level of chloroquine in the erythrocytes of homozygous sickle-cell (SS), normal (AA), and heterozygous (AS) subjects was investigated in vivo and in vitro. Two hours after a single oral dose of chloroquine its level in plasma was consistently lower in SS tha...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1987
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2490867/ https://ncbi.nlm.nih.gov/pubmed/3495366 |
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