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Structural Determinants Underlying the Temperature-sensitive Nature of a Gα Mutant in Asymmetric Cell Division of Caenorhabditis elegans
Heterotrimeric G-proteins are integral to a conserved regulatory module that influences metazoan asymmetric cell division (ACD). In the Caenorhabditis elegans zygote, GOA-1 (Gα(o)) and GPA-16 (Gα(i)) are involved in generating forces that pull on astral microtubules and position the spindle asymmetr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2490787/ https://ncbi.nlm.nih.gov/pubmed/18519563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803023200 |
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