A new APE1/Ref-1-dependent pathway leading to reduction of NF-κB and AP-1, and activation of their DNA-binding activity

APE1/Ref-1 is thought to be a multifunctional protein involved in reduction–oxidation (redox) regulation and base excision DNA repair, and is required for early embryonic development in mice. APE1/Ref-1 has redox activity and AP endonuclease activity, and is able to enhance DNA-binding activity of s...

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Main Authors: Ando, Kozue, Hirao, Satoshi, Kabe, Yasuaki, Ogura, Yuji, Sato, Iwao, Yamaguchi, Yuki, Wada, Tadashi, Handa, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2008
Assuntos:
Molecular Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490748/
https://ncbi.nlm.nih.gov/pubmed/18586825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn416
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