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Selective Constraints in Experimentally Defined Primate Regulatory Regions

Changes in gene regulation may be important in evolution. However, the evolutionary properties of regulatory mutations are currently poorly understood. This is partly the result of an incomplete annotation of functional regulatory DNA in many species. For example, transcription factor binding sites...

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書目詳細資料
Main Authors: Gaffney, Daniel J., Blekhman, Ran, Majewski, Jacek
格式: Artigo
語言:Inglês
出版: Public Library of Science 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490716/
https://ncbi.nlm.nih.gov/pubmed/18704158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000157
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