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Selective Constraints in Experimentally Defined Primate Regulatory Regions

Changes in gene regulation may be important in evolution. However, the evolutionary properties of regulatory mutations are currently poorly understood. This is partly the result of an incomplete annotation of functional regulatory DNA in many species. For example, transcription factor binding sites...

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Detalhes bibliográficos
Main Authors: Gaffney, Daniel J., Blekhman, Ran, Majewski, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490716/
https://ncbi.nlm.nih.gov/pubmed/18704158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000157
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