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Genetic analysis of the adenovirus E4 6/7 trans activator: interaction with E2F and induction of a stable DNA-protein complex are critical for activity.
The adenovirus early E4 transcription unit encodes a 19-kDa polypeptide that trans activates transcription of the early E2 gene and is dependent on the binding sites for the E2F transcription factor. Biochemical assays have shown that the E4 protein, a product of the 6/7 open reading frame, interact...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1991
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC249017/ https://ncbi.nlm.nih.gov/pubmed/1832724 |
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