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The hydrophobic membrane-spanning sequences of the gp52 glycoprotein are required for the pathogenicity of Friend spleen focus-forming virus.

Friend spleen focus-forming virus (SFFV) codes for a transport-defective envelope glycoprotein designated gp52, which is responsible for the leukemogenic properties of the virus. gp52 is a monotopic integral membrane protein anchored in the membrane by a stretch of hydrophobic amino acid residues lo...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Srinivas, R V, Kilpatrick, D R, Tucker, S, Rui, Z, Compans, R W
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1991
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249006/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1895383/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.10.5272-5280.1991
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