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Reduced leukemogenicity caused by mutations in the membrane glycoprotein gene of Rauscher spleen focus-forming virus.

We isolated and characterized two spontaneous, weakly leukemogenic mutants of Rauscher spleen focus-forming virus (R-SFFV) that contain mutations in nonoverlapping regions of the membrane envelope (env) glycoprotein gene. As reported previously (M. Ruta and D. Kabat, J. Virol. 35:844-853, 1980), the...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Machida, C A, Bestwick, R K, Kabat, D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC255478/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6319740/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.49.2.394-402.1984
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