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Zidovudine-resistant human immunodeficiency virus selected by passage in cell culture.

Variants of human immunodeficiency virus (HIV) with reduced sensitivity to zidovudine (3'-azido-3'-deoxythymidine) have been selected by passage of virus in cell culture in the presence of drug. Wild-type, sensitive virus became partially resistant to zidovudine by passage 12 (50% inhibito...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Larder, B A, Coates, K E, Kemp, S D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249001/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1716689/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.10.5232-5236.1991
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