Zidovudine-resistant human immunodeficiency virus selected by passage in cell culture.

Variants of human immunodeficiency virus (HIV) with reduced sensitivity to zidovudine (3'-azido-3'-deoxythymidine) have been selected by passage of virus in cell culture in the presence of drug. Wild-type, sensitive virus became partially resistant to zidovudine by passage 12 (50% inhibitory dose va...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Larder, B A, Coates, K E, Kemp, S D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249001/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1716689/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.10.5232-5236.1991
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