The hepatitis A virus polyprotein expressed by a recombinant vaccinia virus undergoes proteolytic processing and assembly into viruslike particles.

Hepatitis A virus (HAV) contains a single-stranded, plus-sense RNA genome with a single long open reading frame encoding a polyprotein of approximately 250 kDa. Viral structural proteins are generated by posttranslational proteolytic processing of this polyprotein. We constructed recombinant vaccini...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Winokur, P L, McLinden, J H, Stapleton, J T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1651421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.9.5029-5036.1991
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