The hepatitis A virus polyprotein expressed by a recombinant vaccinia virus undergoes proteolytic processing and assembly into viruslike particles.

Hepatitis A virus (HAV) contains a single-stranded, plus-sense RNA genome with a single long open reading frame encoding a polyprotein of approximately 250 kDa. Viral structural proteins are generated by posttranslational proteolytic processing of this polyprotein. We constructed recombinant vaccini...

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Sonraí Bibleagrafaíochta
Main Authors: Winokur, P L, McLinden, J H, Stapleton, J T
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1991
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC248966/
https://ncbi.nlm.nih.gov/pubmed/1651421
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