The full-length E6 protein of human papillomavirus type 16 has transforming and trans-activating activities and cooperates with E7 to immortalize keratinocytes in culture.

The wild-type E6 and E7 genes of human papillomavirus type 16 (HPV16) can cooperate to immortalize normal human keratinocytes in culture. The E6 open reading frame of HPV16 and other HPV types highly associated with cervical cancer has the potential of encoding both full-length E6 and two truncated...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Sedman, S A, Barbosa, M S, Vass, W C, Hubbert, N L, Haas, J A, Lowy, D R, Schiller, J T
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1991
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248945/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1651408/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.9.4860-4866.1991
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