Enzymatic activity of poliovirus RNA polymerase mutants with single amino acid changes in the conserved YGDD amino acid motif.

RNA-dependent RNA polymerases contain a highly conserved region of amino acids with a core segment composed of the amino acids YGDD which have been hypothesized to be at or near the catalytic active site of the molecule. Six mutations in this conserved YGDD region of the poliovirus RNA-dependent RNA...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Jablonski, S A, Luo, M, Morrow, C D
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248910/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1651402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.9.4565-4572.1991
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