The 5' noncoding sequences from a less virulent Theiler's virus dramatically attenuate GDVII neurovirulence.

RNA transcripts derived from recombinant chimeras between the highly virulent GDVII virus and the less virulent BeAn virus were constructed to study the molecular pathogenesis of Theiler's murine encephalomyelitis virus infection. The presence of the BeAn 5' noncoding sequences in chimera...

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Main Authors: Lipton, H L, Calenoff, M, Bandyopadhyay, P, Miller, S D, Dal Canto, M C, Gerety, S, Jensen, K
Formato: Artigo
Idioma:Inglês
Publicado: 1991
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC248876/
https://ncbi.nlm.nih.gov/pubmed/2072455
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