The 5' noncoding sequences from a less virulent Theiler's virus dramatically attenuate GDVII neurovirulence.

RNA transcripts derived from recombinant chimeras between the highly virulent GDVII virus and the less virulent BeAn virus were constructed to study the molecular pathogenesis of Theiler's murine encephalomyelitis virus infection. The presence of the BeAn 5' noncoding sequences in chimera...

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Библиографические подробности
Главные авторы: Lipton, H L, Calenoff, M, Bandyopadhyay, P, Miller, S D, Dal Canto, M C, Gerety, S, Jensen, K
Формат: Artigo
Язык:Inglês
Опубликовано: 1991
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC248876/
https://ncbi.nlm.nih.gov/pubmed/2072455
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