The 5' noncoding sequences from a less virulent Theiler's virus dramatically attenuate GDVII neurovirulence.

RNA transcripts derived from recombinant chimeras between the highly virulent GDVII virus and the less virulent BeAn virus were constructed to study the molecular pathogenesis of Theiler's murine encephalomyelitis virus infection. The presence of the BeAn 5' noncoding sequences in chimera...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Lipton, H L, Calenoff, M, Bandyopadhyay, P, Miller, S D, Dal Canto, M C, Gerety, S, Jensen, K
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1991
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248876/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2072455/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.8.4370-4377.1991
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