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The Leber Congenital Amaurosis Protein AIPL1 Functions as Part of a Chaperone Heterocomplex
PURPOSE: AIPL1 mutations cause the severe inherited blindness Leber congenital amaurosis (LCA). The similarity of AIPL1 to tetratricopeptide repeat (TPR) cochaperones that interact with the chaperone Hsp90 and the ability of AIPL1 to suppress the aggregation of NUB1 fragments in a chaperone-like man...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2488389/ https://ncbi.nlm.nih.gov/pubmed/18408180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.07-1576 |
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