Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level

BACKGROUND: Mortality from colorectal cancer is mainly due to metastatic liver disease. Improved understanding of the molecular events underlying metastasis is crucial for the development of new methods for early detection and treatment of colorectal cancer. Loss of chromosome 8p is frequently seen...

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Hlavní autoři: Macartney-Coxson, Donia P, Hood, Kylie A, Shi, Hong-jun, Ward, Teresa, Wiles, Anna, O'Connor, Rosemary, Hall, David A, Lea, Rod A, Royds, Janice A, Stubbs, Richard S, Rooker, Serena
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488356/
https://ncbi.nlm.nih.gov/pubmed/18590575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-187
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