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Atg8 Controls Phagophore Expansion during Autophagosome Formation

Autophagy is a potent intracellular degradation process with pivotal roles in health and disease. Atg8, a lipid-conjugated ubiquitin-like protein, is required for the formation of autophagosomes, double-membrane vesicles responsible for the delivery of cytoplasmic material to lysosomes. How and when...

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Библиографические подробности
Главные авторы: Xie, Zhiping, Nair, Usha, Klionsky, Daniel J.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488302/
https://ncbi.nlm.nih.gov/pubmed/18508918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-12-1292
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