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Molecular Dissection of the Structural Machinery Underlying the Tissue-invasive Activity of Membrane Type-1 Matrix Metalloproteinase

Membrane type-1 matrix metalloproteinase (MT1-MMP) drives cell invasion through three-dimensional (3-D) extracellular matrix (ECM) barriers dominated by type I collagen or fibrin. Based largely on analyses of its impact on cell function under two-dimensional culture conditions, MT1-MMP is categorize...

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Bibliografiske detaljer
Main Authors: Li, Xiao-Yan, Ota, Ichiro, Yana, Ikuo, Sabeh, Farideh, Weiss, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488283/
https://ncbi.nlm.nih.gov/pubmed/18495869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-01-0016
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