Matrix Metalloproteinases (MMPs) Regulate Fibrin-invasive Activity via MT1-MMP–dependent and –independent Processes

Cross-linked fibrin is deposited in tissues surrounding wounds, inflammatory sites, or tumors and serves not only as a supporting substratum for trafficking cells, but also as a structural barrier to invasion. While the plasminogen activator-plasminogen axis provides cells with a powerful fibrinolyt...

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Autores principales: Hotary, Kevin B., Yana, Ikuo, Sabeh, Farideh, Li, Xiao-Yan, Holmbeck, Kenn, Birkedal-Hansen, Henning, Allen, Edward D., Hiraoka, Nobuaki, Weiss, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2002
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193588/
https://ncbi.nlm.nih.gov/pubmed/11828004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20010815
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