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Ubiquitination of Fibroblast Growth Factor Receptor 1 Is Required for Its Intracellular Sorting but Not for Its Endocytosis

Endocytosis and targeting of growth factor receptors for lysosomal degradation have been associated with ubiquitination of the intracellular part of the receptors. To elucidate the role of receptor ubiquitination in internalization and sorting of fibroblast growth factor receptor (FGFR), we construc...

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Autori principali: Haugsten, Ellen Margrethe, Małecki, Jędrzej, Bjørklund, Sunniva Maria Stordal, Olsnes, Sjur, Wesche, Jørgen
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488279/
https://ncbi.nlm.nih.gov/pubmed/18480409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-12-1219
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