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Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes.

All presently available replication-competent proviral clones of human immunodeficiency virus type 1 (HIV-1) are derived from cell culture-amplified virus. Since tissue culture is highly selective for viral strains with an in vitro growth advantage, such clones may not be representative of the biolo...

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Bibliographic Details
Published in:J Virol
Main Authors: Li, Y, Kappes, J C, Conway, J A, Price, R W, Shaw, G M, Hahn, B H
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1991
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248827/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1830110/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.8.3973-3985.1991
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