Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes.

All presently available replication-competent proviral clones of human immunodeficiency virus type 1 (HIV-1) are derived from cell culture-amplified virus. Since tissue culture is highly selective for viral strains with an in vitro growth advantage, such clones may not be representative of the biolo...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Li, Y, Kappes, J C, Conway, J A, Price, R W, Shaw, G M, Hahn, B H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248827/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1830110/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.8.3973-3985.1991
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