Nitroalkenes Suppress Lipopolysaccharide-Induced Signal Transducer and Activator of Transcription Signaling in Macrophages: A Critical Role of Mitogen-Activated Protein Kinase Phosphatase 1

Nitration products of unsaturated fatty acids are formed via NO-dependent oxidative reactions and appear to be a new class of endogenous antiinflammatory mediators. Nitroalkene derivatives of nitrated linoleic acid (LNO(2)) and nitrated oleic acid (OA-NO(2)) alleviate inflammatory responses in macro...

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Autores principales: Ichikawa, Tomonaga, Zhang, Jifeng, Chen, Kai, Liu, Yusen, Schopfer, Francisco J., Baker, Paul R. S., Freeman, Bruce A., Chen, Yuqing E., Cui, Taixing
Formato: Artigo
Lenguaje:Inglês
Publicado: The Endocrine Society 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488206/
https://ncbi.nlm.nih.gov/pubmed/18467446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1639
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